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Filtered Search Results
Medchemexpress LLC Zastaprazan (JP-1366) | 2133852-18-1 | 100.0% | 362.47 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Zastaprazan (JP-1366) is a proton pump inhibitor and a potent potassium-competitive acid blocker. It can be used in the research of gastrointestinal inflammatory diseases or gastric acid-related diseases such as gastroesophageal reflux disease.
- IC50 & Target: proton pump
- In vitro: Is a proton pump inhibitor
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Aloe-emodin-8-O-β-D-glucopyranoside | 33037-46-6 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Aloe-emodin-8-O-β-D-glucopyranoside is a chemical compound primarily used as a laboratory reagent. Isolated from *Saussurea lappa*, it acts as a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC₅₀ of 26.6 μM. This compound is intended for research purposes only.
- Moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B)
- Isolated from *Saussurea lappa*
- Exhibits cytotoxicity against MDR1 Pgp under-expressing human HCT116 cells (IC₅₀ 75 μM)
- Exhibits cytotoxicity against MDR1 Pgp overexpressing human HepG2 cells (IC₅₀ > 100 μM)
- High purity of 99.67%
- Solid appearance with light yellow to yellow color
- Molecular formula C₂₁H₂₀O₁₀
- Molecular weight of 432.38
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Matrix Scientific 2-(TRICHLOROACETYL)PYRROLE-25G
2-(Trichloroacetyl)pyrrole, 97%; 25g,C6H4Cl3NO, MFCD00128757, mw 212.46, [35302-72-8]
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Pfaltz & Bauer Anthraquinone-2 7-disulfonic A| 25g| 853-67-8
Anthraquinone-2 7-disulfonic A| 25g| 853-67-8
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC YK-3-237 | 1215281-19-8 | 99.5% | 372.18 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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YK-3-237 is a SIRT1 activator that targets mutant p53 and inhibits the proliferation of triple-negative breast cancer cells. This compound offers a potent and selective approach to cancer research with several key activities:
- Exhibits anti-proliferative activities toward most breast cancer cell lines at submicromolar concentration.
- Preferentially inhibits the proliferation of breast cancer cell lines carrying mtp53.
- Inhibits the proliferation of triple-negative breast cancer (TNBC) cell lines.
- Deacetylates mtp53 in TNBC cell lines.
- Potent activator of Sirt1.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Laflunimus | 147076-36-6 | MFCD28502173 | 99.7% | 310.27 | C15H13F3N2O2 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Laflunimus is an immunosuppressive research compound and an analogue of the leflunomide-active metabolite A77 1726. It functions as an orally active inhibitor of dihydroorotate dehydrogenase (DHODH) and also inhibits prostaglandin endoperoxide H synthase (PGHS)-1 and -2; it suppresses immunoglobulin secretion with low micromolar potency.
- High purity suitable for research applications.
- Inhibits DHODH for studies of pyrimidine synthesis and immunomodulation.
- Suppresses IgM and IgG secretion at low micromolar concentrations.
- Also inhibits PGHS-1 and PGHS-2, supporting inflammation pathway research.
- Available as solid and as a solution for flexible experimental use.
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eMolecules 200052-70-6 | Ambeed | 4-(Dicyanomethylene)-2-tert-butyl-6-(1177-tetramethyljulolidin-4-yl-vinyl)-4H-pyran | 100mg | 665578908 | A417663 | 453.63 | C30H35N3O
Ambeed | 246-Tris(3-(1H-pyrazol-1-yl)phenyl)-135-triazine | 100mg | 650568628 | A1486653 | 352196-01-1 | 507.561 | C30H21N9
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eMolecules 83502-55-0 | 1-Acetyl-4-(2-hydroxyethyl)piperazine | Combi-Blocks | MFCD02585155 | 172.228 | C8H16N2O2 | 97.000 | CC(=O)N1CCN(CCO)CC1 | 1g | 232307030
1-Acetyl-4-(2-hydroxyethyl)piperazine | Combi-Blocks | 83502-55-0 | MFCD02585155 | 172.228 | C8H16N2O2 | 97.000 | CC(=O)N1CCN(CCO)CC1 | 1g | 232307030
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eMolecules 515135-65-6 | 5-Bromo-2-fluoro-4-methylbenzoic acid | Combi-Blocks | MFCD23712067 | 233.036 | C8H6BrFO2 | 98.000 | Cc1cc(F)c(cc1Br)C(O)=O | 1g | 267160673
5-Bromo-2-fluoro-4-methylbenzoic acid | Combi-Blocks | 515135-65-6 | MFCD23712067 | 233.036 | C8H6BrFO2 | 98.000 | Cc1cc(F)c(cc1Br)C(O)=O | 1g | 267160673
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eMolecules 1671-75-6 | Heptanophenone | MFCD00009539 | 25g
Pharmablock | 2-[3-fluoro-5-(trifluoromethyl)phenyl]acetonitrile | 25mg | 761745286 | PBTHL0145 | 239087-12-8 | MFCD00061181 | 203.140 | C9H5F4N
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Medchemexpress LLC (R)-N-(3-(4-(Methoxymethyl)-6-(3-methoxytetrahydrofuran-3-yl)pyridin-2-yl)-1-(oxetan-3-yl)-1H-pyrro... | 2368945-27-9 | 99.9% | 452.50 | C24H28N4O5 | 10 MG
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ABBV-712 is a selective, orally active inhibitor of tyrosine kinase 2 (TYK2) developed as a clinical candidate for research into autoimmune and inflammatory diseases. It stabilizes the TYK2 pseudokinase (JH2) domain and demonstrates anti-inflammatory activity in preclinical models.
- Selective TYK2 inhibition suitable for signaling and pharmacology studies.
- Demonstrated anti-inflammatory activity in animal disease models.
- High analytical purity for biochemical and cellular assays.
- High solubility in DMSO (250 mg/mL) for concentrated stock solutions.
- Available in small research pack sizes for dose-response testing.
- Recommended storage: powder at -20°C for long term, 4°C for short term.
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eMolecules 10531-43-8 | 2-bromo-1-(5-phenyl-2-thienyl)-1-ethanone | Maybridge BB | MFCD02681997 | 281.170 | C12H9BrOS | 95.000 | BrCC(=O)c1ccc(s1)-c1ccccc1 | 1g | 333083086
2-bromo-1-(5-phenyl-2-thienyl)-1-ethanone | Maybridge BB | 10531-43-8 | MFCD02681997 | 281.170 | C12H9BrOS | 95.000 | BrCC(=O)c1ccc(s1)-c1ccccc1 | 1g | 333083086
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Medchemexpress LLC Obeldesivir | 2647441-36-7 | 99.5% | 361.35 g/mol | C16H19N5O5 | 5 MG
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Obeldesivir is an orally active ester prodrug of GS-441524 developed for antiviral research. It inhibits replication of SARS-CoV-2 in vitro and is supplied as a high-purity research chemical with defined storage and solubility properties for laboratory use.
- Orally active antiviral ester prodrug of GS-441524.
- High purity suitable for research applications.
- White to off-white solid appearance.
- Soluble in DMSO at high concentration.
- Specified storage conditions for solid and solvent solutions.
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Medchemexpress LLC VB124 | 2230186-18-0 | 99.9% | 426.89 | 50 MG
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VB124 is an orally active, potent, and selective MCT4 inhibitor. It specifically inhibits lactate efflux in MDA-MB-231 cells with IC50s of 8.6 nM for lactate import and 19 nM for lactate export. Highly selective for MCT4 over MCT1, this compound is suitable for research into cardiac hypertrophy, heart failure, and metabolism.
- Specifically inhibits lactate efflux
- Highly selective for MCT4 over MCT1
- Inhibits cell proliferation
- Attenuates cardiac hypertrophy in mice
- No overt toxicities observed in tested animal models
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eMolecules 4'-Methoxy-3'-(trifluoromethyl)acetophenone | Combi-Blocks | 149105-10-2 | MFCD01091010 | 218.175 | C10H9F3O2 | 98.000 | COc1ccc(cc1C(F)(F)F)C(C)=O | 1g | 232312844
4'-Methoxy-3'-(trifluoromethyl)acetophenone | Combi-Blocks | 149105-10-2 | MFCD01091010 | 218.175 | C10H9F3O2 | 98.000 | COc1ccc(cc1C(F)(F)F)C(C)=O | 1g | 232312844
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